By Lisa Richwine

LOS ANGELES (Reuters) - Virtual reality has yet to take off with the bulk of video gamers, but the industry is doubling down on its bet that one day it will.

At the annual E3 video game showcase in Los Angeles this week, attendees strapped on VR headsets to peer into fantasy worlds, battle robotic creatures and command starships. Meanwhile, game publishers announced investments that showed they believe VR is ready to go mainstream.

"This is clearly the coming-out party for VR," said P.J. McNealy, chief executive officer and founder of Digital World Research. "The interest is there, the hardware is coming to market, and the content developers are figuring out how to take advantage of it."

E3, or the Electronic Entertainment Expo, is an annual spectacle devoted to serious gaming. Sales of games played on consoles or PCs still lead the $99.6 billion global gaming industry, according to data from research firm Newzoo. But an explosion in mobile games, plus a shift toward virtual reality hardware and software, could change that.

Sony Corp unveiled a $399 PlayStation VR headset at E3 that will hit stores in October. Fifty games will be available by year's end, including VR versions of blockbuster franchises "Resident Evil" and "Batman."

Some games will be exclusive to PlayStation VR, including "Star Wars: Battlefront X-Wing VR Mission." Star Trek fans can command a Starfleet vessel "Star Trek: Bridge Crew," which will be playable on PlayStation VR, Facebook's (FB.O) Oculus Rift headset, and the HTC (2498.TW) Vive VR device.

Microsoft Corp (MSFT.O) let potential buyers know that it will have a new version of its Xbox, dubbed Project Scorpio, that will support VR in time for the 2017 holiday season. The company is also is developing its HoloLens augmented reality glasses, which overlay images as holograms onto a user's real-life field of vision.

Many in the industry are still skeptical about VR's potential. They question how many gamers will shell out hundreds of dollars for a headset after investing in a gaming console.

"We're going to find out what's good and bad about virtual reality in the months and years to come," said Steve Boxer, a gaming journalist from Britain who tried out games at E3.

"Personally I don't want to have to sit there wearing a virtual reality helmet for more than 20 minutes."

Sony is working with developers to adapt console games to a VR environment, said John Koller, a vice president for Sony Interactive Entertainment America.

"VR is going to be shorter, very intense bursts," Koller said. "We see it chopped up into these experiences that are very exciting and emotionally driven."