U.S. Senate goes 'nuclear,' ends Democrats' blockade of Trump court pick

* Senate votes 52-48 to change venerable filibuster rule

* Gorsuch's confirmation vote expected on Friday

* He would restore Supreme Court's conservative majority (Adds expected timing of final vote)

By Lawrence Hurley and Andrew Chung

WASHINGTON, April 6 (Reuters) - Senate Republicans on Thursday crushed a Democratic blockade of President Donald Trump's U.S. Supreme Court nominee in a fierce partisan brawl, approving a rule change dubbed the "nuclear option" to allow for conservative judge Neil Gorsuch's confirmation by Friday.

With ideological control of the country's highest court at stake, the Republican-led Senate voted 52-48 along party lines to change its long-standing rules in order to prohibit a procedural tactic called a filibuster against Supreme Court nominees. That came after Republicans failed by a 55-45 tally to muster the 60-vote super-majority needed to end the Democratic filibuster that had sought to deny Gorsuch confirmation to the lifetime post.

The Senate's action cleared the way to confirm Gorsuch by simple majority on Friday, with a final vote expected by late morning. Republicans control the Senate 52-48. The rule change was called the "nuclear option" because it was considered an extreme break with Senate tradition.

Trump had encouraged Republican Senate Majority Leader Mitch McConnell to "go nuclear." Confirmation of Gorsuch would represent Trump's first major victory since taking office on Jan. 20, after setbacks on healthcare legislation and the blocking of his order that sought to ban travelers from several Muslim-majority countries from entering the United States.

Senate confirmation of Gorsuch, a Colorado-based federal appeals could judge, would restore the nine-seat court's 5-4 conservative majority, enable Trump to leave an indelible mark on America's highest judicial body and fulfill a top campaign promise by the Republican president. Gorsuch, 49, could be expected to serve for decades.

"This will be the first and last partisan filibuster of the Supreme Court," McConnell said on the Senate floor, accusing Democrats of trying to inflict political damage on Trump and to keep more conservatives from joining the high court.

"In 20 or 30 or 40 years, we will sadly point to today as a turning point in the history of the Senate and the Supreme Court, a day when we irrevocably moved further away from the principles our founders intended for these institutions: principles of bipartisanship, moderation and consensus," Senate Democratic leader Chuck Schumer said on the Senate floor.

Schumer ridiculed McConnell's contention that the Democratic action was unprecedented. He noted that the Republican-led Senate refused last year to consider Democratic former President Barack Obama's nomination of appellate judge Merrick Garland for the same seat that Trump selected Gorsuch to fill.