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Syra Health Announces Positive Preliminary Results from Syrenity Study Led by Indiana University

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CARMEL, Ind., Feb. 18, 2025 /PRNewswire/ -- Syra Health Corp. (NASDAQ: SYRA) ("Syra Health" or the "Company"), a healthcare technology company powering better health by providing meaningful solutions, announced today positive preliminary results from the clinical research study being conducted by Indiana University (IU) of its flagship mental health product, Syrenity.

Syra Health - A catalyst for improving health outcomes. (PRNewsfoto/Syra Health)
Syra Health - A catalyst for improving health outcomes. (PRNewsfoto/Syra Health)

A randomized clinical research study to test the efficacy of the Syrenity app is being led by Dr. Lorenzo-Luaces, principal investigator and associate department chair of Psychological and Brain Sciences at IU. The IRB-approved study enrolled approximately 135 people who expressed symptoms of moderate or more severe depression. Of the 135 people, 63 were provided access to Syrenity versus 72 people without access. The preliminary analysis of the six-week study suggested trends toward reductions in depression symptoms among Syrenity users compared to those without access to the app. Preliminary trends in overall well-being were also observed, alongside indications of increased cognitive reappraisal—or the ability to mentally reframe experiences to avoid negative emotions. There were also signs of improvement in emotion suppression (expressive suppression), an unhealthy coping strategy where a person hides their feelings to try and make themselves feel better. Participants who used the Syrenity app were more likely to show their emotions in a healthy way than non-app users.

"I'm very excited about the app because it's one of fewer than 5% of mental health apps based on science and is being tested for its scientific merit," said Dr. Lorenzo-Luaces. "What also sets it apart from many others, is that it targets more than one mental health challenge. People often suffer from multiple conditions, such as both depression and anxiety and the app's ability to address both allows it to help many more people."

A second clinical research study with additional users will be conducted in due course to test the statistical significance of these results. A detailed analysis of engagement measures and a qualitative analysis of users will be performed to further understand the app's efficacy. The results of these analyses will help in developing additional modules, new features, and activities targeting various behavioral and mental health issues.

Of the study participants, roughly two-thirds were women, approximately 30% were racial-ethnic minorities, and about half had a bachelor's degree or higher level of education. About 36% of the study group had yearly household incomes between $50,000 to $100,000 and 30% were unemployed at the time of the study. Most participants were not in therapy.