HONG KONG (AP) — Asian stocks were mostly lower on Tuesday, despite gains on Wall Street, as worries mounted over escalations in the Russia-Ukraine war.

U.S. futures edged higher while oil prices were little changed.

On Tuesday, Ukraine fired several American-supplied longer-range missiles into Russia, according to the official, marking the first such use in nearly 1,000 days of war. On the same day, Russian President Vladimir Putin formally lowered the threshold for Russia’s use of its nuclear weapons.

In Japan, the Nikkei 225 slipped 0.2% to 38,352.34 after the Finance Ministry reported the country recorded a trade deficit in October, for a fourth straight month. Exports rose 3.1% from a year earlier as a weak yen and the rising price of energy kept import costs high. A trade deficit occurs when the country is importing more goods and services than it is exporting.

Shares of Seven & i Holdings Co., the company that owns over 80,000 7-Eleven convenience stores worldwide, soared 8.4% on Wednesday after local media reported that the founding family plans to raise over 8 trillion yen ($51.66 billion) to take the company private within this financial year.

China's central bank announced it will keep its benchmark lending rates unchanged after it cut its one-year lending rate to 3.1% in October. Hong Kong’s Hang Seng edged 0.1% higher to 19,687.10, and the Shanghai Composite gained 0.1% to 3,979.15.

Australia’s S&P/ASX 200 dipped 0.6% to 8,326.30. South Korea’s Kospi added 0.4% to 2,482.29.

On Tuesday, the S&P 500 rose 0.4% to 5,916.98 after erasing an early drop of 0.7%. The Nasdaq composite also shook off an early loss to turn 1% higher to 18,987.47, while the Dow Jones Industrial Average slipped 0.3% to 43,268.94.

Nvidia’s 4.9% climb accounted for most of the index’s gain. The chip company’s stock rallied ahead of its profit report for the latest quarter, which is coming later Wednesday, and vaulted its gain for the year to nearly 197% thanks to the craze around artificial-intelligence technology.

The worries on the Ukraine-Russia conflict sent investors into U.S. Treasury bonds, which are seen as some of the world’s safest investments. The rise in their prices in turn lowered their yields, and the 10-year Treasury yield fell to 4.39% from 4.41% late Monday.

Gold also rose 0.6% and recovered some of the losses it sustained following Donald Trump’s victory in the U.S. presidential election, as investors herded into places traditionally considered safer during times of trouble.

Walmart climbed 3% after topping forecasts for both profit and revenue. The nation’s biggest retailer said it saw broad-based strength across its categories, including sales made both online and in stores. It also said it served more upper-income households, while raising its forecasts for sales and profit for the full year.