QT Imaging Granted Renewal of NIH Sponsored Study for Early Identification of Response of Breast Cancer Patients to Neoadjuvant Chemotherapy

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NOVATO, Calif., October 29, 2024--(BUSINESS WIRE)--QT Imaging Holdings, Inc. (NASDAQ:QTI) a medical device company engaged in research, development, and commercialization of innovative body imaging systems, is pleased to announce the third year renewal of its five-year research grant from the National Institutes of Health (NIH)/National Cancer Institute (NCI). The study is a collaboration with the Department of Radiation Oncology, the Radiation Treatment Program at the Sunnybrook Health Sciences Centre in Toronto, Canada, the largest cancer center in Canada, and The University of Illinois, Urbana-Champaign, Department of Electrical and Computer Engineering and Grainger College of Engineering.

As reported in the past, the goal of the project is to develop an accurate, quantitative, portable, safe, and repeatable breast imaging approach for early identification of the response of breast cancer patients to neoadjuvant chemotherapy (NAC). As part of this grant, quantitative breast images with independent biomarkers known to be sensitive to cancer were to be collected, and the response of cancer to therapy was planned to be derived from quantitative ultrasound based on backscatter analysis.

The QTI Breast Acoustic CT™ System installed at Sunnybrook Health Sciences Center earlier in the year was used to collect high resolution breast images from female patients with independent biomarkers known to be sensitive to cancer. The backscatter analysis method was successfully tested on in vivo breast imaging data. As for the next steps, the team will incorporate the algorithms into the QTI image reconstruction flow through combined algorithms and apply AI/ML techniques to yield an improved estimate of NAC efficacy based on the quantitative biomarkers from QTI scans data and backscatter analysis. As these quantitative biomarkers were never before available with an imaging scan, they generate fertile ground for novel AI/ML development.

"We are very encouraged by the results of our study and are privileged to work with Michael Oelze, PhD at Illinois, Greg Czarnota, MD, PhD at Sunnybrook Health Sciences Centre," said Dr. James Wiskin, PhD, Principal Data Scientist and QTI Fellow. "The renewal of this grant is a reaffirmation of the need to determine effective therapies that work efficiently in days instead of months in cancer patients. The ongoing research holds the promise of yielding additional quantitative markers with improved estimate precision not afforded by conventional ultrasound imaging modalities."