New York City’s iconic 21 Club, despite remaining a mainstay of the Big Apple's social scene for nearly a century, is the latest bar and restaurant to fall victim to the coronavirus pandemic.

The former speakeasy first opened during the Prohibition era, and has counted presidents, athletes, renouned artists and many more high-profile guests among its clientele throughout the years.

But that’s coming to an end, according to a tweet from CNBC reporter David Faber Friday afternoon.

A spokeswoman for the restaurant’s parent company said it had been temporarily closed since March to protect its patrons and employees during the coronavirus pandemic and that the owners wanted to reopen in the future but could not yet say how or when.

"In light of the ongoing global crisis and anticipated extended recovery period for the hospitality industry, the difficult decision was made that it will not be feasible to reopen the 21 Club in its current form for the foreseeable future," Ülkü Eruçar-Kenny, the spokeswoman, told Fox News Saturday. "The company is exploring potential opportunities that will allow 21 Club to remain a viable operation in the long term, while retaining its distinctive character."

The famous restaurant told New York labor officials Wednesday it planned to cease operations "indefinitely," the New York Times reported.

"At this early stage, we are not ready to announce any final concept or timeframe," Eruçar-Kenny said Saturday. "But the vision is that 21 Club will always remain an important social and cultural hub and icon of New York, one that is well positioned to fulfill its role in the City’s exciting future when the time comes.

The five-story restaurant’s eye-catching entrance way on 21 W. 52nd St., is adorned by 35 jockey statues. It has been closed for most of the coronavirus pandemic.

It boasts having served historic figures ranging from past presidents to the Nobel-winning novelist Ernest Hemingway to tennis legend John McEnroe.

INSIDE NEW YORK CITY'S 21 CLUB: A PRESIDENTIAL DINING TRADITION

After Prohibition agents raided it in 1930, the restaurant’s owners hired an architect to build in camouflaged doors, secret chutes and even “quick-release bar shelves,” according to the restaurant’s website. That was the last time it was caught operating as a speakeasy.

The restaurant's wall art includes pieces from Frederick Remington and McClelland Barclay, and Walt Disney and Peter Arnor, of the New Yorker, have given cartoon dedications. It also has modern collections from Francesca Anderson and Wynne Evans. Its Bar Room has mementos from former Presidents John F. Kennedy and Bill Clinton, tennis racquets from McEnroe and Chris Evert, and a baseball bat from Hall of Famer Willie Mays. It's reportedly hosted every sitting president since Franklin D. Roosevelt, aside from George W. Bush and Barack Obama.