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Pfizer (NYSE:PFE) Misses Q1 Revenue Estimates
PFE Cover Image
Pfizer (NYSE:PFE) Misses Q1 Revenue Estimates

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Global pharmaceutical company Pfizer (NYSE:PFE) missed Wall Street’s revenue expectations in Q1 CY2025, with sales falling 7.8% year on year to $13.72 billion. The company’s full-year revenue guidance of $62.5 billion at the midpoint came in 0.7% below analysts’ estimates. Its non-GAAP profit of $0.92 per share was 35.2% above analysts’ consensus estimates.

Is now the time to buy Pfizer? Find out in our full research report.

Pfizer (PFE) Q1 CY2025 Highlights:

  • Revenue: $13.72 billion vs analyst estimates of $13.94 billion (7.8% year-on-year decline, 1.6% miss)

  • Adjusted EPS: $0.92 vs analyst estimates of $0.68 (35.2% beat)

  • The company reconfirmed its revenue guidance for the full year of $62.5 billion at the midpoint

  • Management reiterated its full-year Adjusted EPS guidance of $2.90 at the midpoint

  • Operating Margin: 21.7%, down from 31.6% in the same quarter last year

  • Organic Revenue rose 6% year on year (-19% in the same quarter last year)

  • Market Capitalization: $130.7 billion

Company Overview

With roots dating back to 1849 when two German immigrants opened a fine chemicals business in Brooklyn, Pfizer (NYSE:PFE) is a global biopharmaceutical company that discovers, develops, manufactures, and sells medicines and vaccines for a wide range of diseases and conditions.

Sales Growth

A company’s long-term performance is an indicator of its overall quality. Even a bad business can shine for one or two quarters, but a top-tier one grows for years. Unfortunately, Pfizer’s 5.2% annualized revenue growth over the last five years was mediocre. This was below our standard for the healthcare sector and is a tough starting point for our analysis.

Pfizer Quarterly Revenue
Pfizer Quarterly Revenue

We at StockStory place the most emphasis on long-term growth, but within healthcare, a half-decade historical view may miss recent innovations or disruptive industry trends. Pfizer’s performance shows it grew in the past but relinquished its gains over the last two years, as its revenue fell by 18.1% annually.

Pfizer Year-On-Year Revenue Growth
Pfizer Year-On-Year Revenue Growth

We can dig further into the company’s sales dynamics by analyzing its organic revenue, which strips out one-time events like acquisitions and currency fluctuations that don’t accurately reflect its fundamentals. Over the last two years, Pfizer’s organic revenue averaged 11.6% year-on-year declines. Because this number is better than its normal revenue growth, we can see that some mixture of divestitures and foreign exchange rates dampened its headline results.

Pfizer Organic Revenue Growth
Pfizer Organic Revenue Growth

This quarter, Pfizer missed Wall Street’s estimates and reported a rather uninspiring 7.8% year-on-year revenue decline, generating $13.72 billion of revenue.