Nautilus Biotechnology Inc (NAUT) Q3 2024 Earnings Call Highlights: Strategic Advances and ...

In This Article:

  • Total Operating Expenses: $19.1 million for Q3 2024, roughly equal to Q3 2023, and $1.7 million below last quarter.

  • Research and Development Expenses: $12.3 million in Q3 2024, compared to $12.0 million in the prior year period.

  • General and Administrative Expenses: $6.8 million in Q3 2024, compared to $7.1 million in the prior year period, and $1.5 million below last quarter.

  • Net Loss: $16.4 million for Q3 2024, compared to $15.9 million in the prior period.

  • Headcount: 161 at the end of Q3 2024, roughly flat compared to 160 in Q3 2023.

  • Cash, Cash Equivalents, and Investments: $221.2 million at the end of Q3 2024, compared to $232.9 million at the end of last quarter.

  • Cash Burn: $11.7 million for Q3 2024, benefiting from a $1.3 million shift in unrealized losses to an unrealized gain position.

  • Operating Expense Growth Guidance: Expected to be roughly 10% for the full year 2024, better than previous guidance of 15-20%.

  • Cash Runway: Extended into 2027.

Release Date: October 29, 2024

For the complete transcript of the earnings call, please refer to the full earnings call transcript.

Positive Points

  • Nautilus Biotechnology Inc (NASDAQ:NAUT) has made significant progress in developing its proteomics platform, particularly in detecting proteoforms, which could have substantial implications for biomarker discovery and drug development.

  • The company has demonstrated a scalable and reliable process for building flow cells and chips, and robust single molecule deposition, which are crucial for their platform's success.

  • Nautilus Biotechnology Inc (NASDAQ:NAUT) has successfully integrated all aspects of their assay and platform, indicating readiness for commercial availability in the near future.

  • The company has managed its resources efficiently, maintaining a flat headcount while significantly increasing experimental capacity and output.

  • Nautilus Biotechnology Inc (NASDAQ:NAUT) has a strong cash position with $221.2 million in cash, cash equivalents, and investments, extending their cash runway into 2027.

Negative Points

  • Nautilus Biotechnology Inc (NASDAQ:NAUT) is behind on its internal milestones for broad scale discovery, specifically in quantifying a significant number of proteins from complex samples.

  • The fallout rate for probe candidates is currently too high, indicating challenges in transitioning probe candidates to platform-ready probes.

  • The company has not yet achieved its goal of decoding 500 to 2000 proteins from cell lysate, a critical milestone for their broad scale platform.

  • There is uncertainty regarding the exact timeline for achieving key development milestones, such as the broad scale milestone by the US HUPO conference.

  • Nautilus Biotechnology Inc (NASDAQ:NAUT) faces potential challenges in breaking into the market with established players like Astral and Ultra 2, which have gained traction in the proteomics space.