IART Stock to Gain From New Study Findings on DuraSeal Dural Sealant

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Integra LifeSciences Holding Corporation IART has announced the publication of a new economic study assessing the budget impact of switching treatment from fibrin glue to DuraSeal Polyethylene Glycol (“PEG”) hydrogel in five major European countries. The findings show an average cost savings of €419 to €1,279 per patient, with a consistent cost reduction averaging around 22% per procedure across Belgium, France, Germany and the United Kingdom, and 15% in Italy.

The study, “PEG hydrogel sealant versus fibrin glue in posterior fossa surgery: An economic comparison across five European countries,” was published in the Journal of Comparative Effectiveness Research in February 2024.

Predicting IART Stock Movement Following the News

After the announcement on Nov. 13, IART shares plunged 6.1%, finishing at $23.31 yesterday. On a promising note, the latest development is expected to boost the international business of the company’s Codman Specialty Surgical (“CSS”) segment, which has been benefiting from the rapid acceptance of global neurosurgery line-ups, including CSS management and neuromonitoring. We expect the market sentiment surrounding the IART stock to remain positive surrounding this news.

Integra currently has a market capitalization of $1.91 billion. According to the Zacks Consensus Estimate, the company’s 2024 sales are expected to improve by 4.6% compared to last year. It delivered an earnings beat of 1.41%, on average, in the trailing four quarters.

More on the Study Supporting Integra

Cerebrospinal fluid (CSF) leaks after posterior cranial fossa (PCF) surgery are a significant cause of longer hospital stays, hospital readmissions and other costly post-surgical interventions. The current practice of sealing the operative site after primary closure to aid the healing process and protect the patient from CSF leaks widely relies on fibrin glue or PEG hydrogel.

The published economic analysis, based on a peer-reviewed prospective observational study of 200 patients, found that PEG hydrogel was associated with positive clinical outcomes compared to fibrin glue in PCF surgeries. A decision tree was developed on a previous U.S. model and input costs that were derived from European country-specific published sources. The results indicated that Integra’s DuraSeal Dural Sealant is more clinically effective than fibrin glue at preventing CSF leaks after PCF surgery, which may help hospitals reduce costs. The system is meant for use as an adjunct to standard methods of dural repair as sutures to provide watertight closure.