Denali Therapeutics price target lowered to $42 from $50 at Oppenheimer

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Tue, Mar 4, 2025, 6:00 AM 1 min read

Oppenheimer analyst Jay Olson lowered the firm’s price target on Denali Therapeutics (DNLI) to $42 from $50 and keeps an Outperform rating on the shares following quarterly results and after hosting CEO Ryan Watts at the firm’s 35th Annual Healthcare Conference. Oppenheimer remains optimistic about the multiple opportunities ahead. Near term, it anticipates imminent filing for DNL310 in Hunter syndrome and suspect a high likelihood for priority review; additional regulatory and clinical updates should further boost investor confidence in the iterability of Denali’s ETV platform as the company is expanding the franchise to address more common diseases. The firm updated its model, lowering the probability of success for DNL343 for ALS while adding DNL126.

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