What to know about the newly discovered COVID-19 variant, according to a Johns Hopkins researcher

The recent announcement by South African scientists of a new COVID-19 variant has sparked fears across the globe, leading to a market sell-off and heightened anxiety about a pandemic entering its second winter.

The variant, currently referred to as B.1.1.529, was discovered in Botswana and has already been reported in South Africa, Belgium, Hong Kong, and Israel.

There have been numerous variants since the coronavirus first emerged, but the B.1.1.529 has drawn considerable attention because of how significantly it has mutated.

“What it has is a cluster of several mutations, more mutations than we’ve seen in that spike protein part of the coronavirus, and the spike protein is important because that’s what our vaccines target,” Amesh Adalja, senior scholar at the Johns Hopkins Center for Health Security, said on Yahoo Finance Live (video above). “That’s how the virus enters ourselves.”

Following the discovery, the World Health Organization (WHO) officially declared B.1.1.529 a "variant of concern" on Friday and later named the variant omicron.

“When we see mutations there, and there are some that are concerning, we worry: Is this more transmissible? Is this something that might be able to escape some of our vaccine protection? Is this something that might escape monoclonal antibody protection?” Adalja said. “All of these questions are going to be answered in the next couple of days or weeks, and that will allow us to fully characterize how much we should worry about this.”

People leave the Regal Airport Hotel at Chek Lap Kok airport in Hong Kong on November 26, 2021, where a new Covid-19 variant deemed a 'major threat' was detected in a traveller from South Africa and who has since passed it on to a local man whilst in quarantine. (Photo by Peter PARKS / AFP) (Photo by PETER PARKS/AFP via Getty Images)
People leave the Regal Airport Hotel at Chek Lap Kok airport in Hong Kong on November 26, 2021, where a new Covid-19 variant deemed a 'major threat' was detected in a traveller from South Africa and who has since passed it on to a local man whilst in quarantine. (Photo by Peter PARKS / AFP) · PETER PARKS via Getty Images

The three dimensions

Dr. Lakshman Swamy, an ICU physician at Boston Medical Center, said that while there are reasons for concern, it’s not time to panic yet.

“There are three dimensions to this,” Swamy said on Yahoo Finance Live. “The first is: Is this variant going to spread more quickly, more like wildfire than Delta? Is it going to overtake Delta?”

He noted that “there’s a reason we’re all talking” about this current variant and that it should be closely examined to see how similar it is to the highly contagious Delta strain, which now accounts for almost all current COVID cases in the U.S.

The other two important questions to ask, Swamy said, are: Will it hurt and kill a lot of people? And will current vaccines work against it?

“I think we have nowhere near the numbers to know that right now,” Swamy said, but added that concerns over the effectiveness of the vaccines are valid. “There’s reason to worry because of the new mutations in the spike protein… but there’s no reason to assume our vaccines won’t offer significant protection there.”