(Adds details on damage to wine industry)

By Christina Farr and Robin Respaut

NAPA, Calif., Aug 25 (Reuters) - A strong earthquake that jolted residents of California's Napa Valley wine country from their beds on Sunday caused insured property damage likely in the hundreds of millions of dollars, but the region's total economic losses will be several times that, experts said on Monday.

The magnitude 6.0 quake, the biggest to hit California's Bay Area in 25 years, struck before dawn on Sunday near Napa, injuring more than 200 people and damaging dozens of buildings in the picturesque community northeast of San Francisco.

At least 49 buildings in Napa, a town of 77,000 residents, were "red-tagged" as unsafe to enter, including the Napa Senior Center and the local courthouse, and that figure was expected to rise as additional structures were inspected, officials said.

The quake struck just as the grape-harvesting season was getting under way in Napa County, a significant wine-producing area that generates thousands of jobs in a region famed for its Cabernet Sauvignon, Pinot Noir, Chardonnay and Sauvignon Blanc.

The full extent of industry damage had yet to be assessed, but one Napa winery spokesman said the quake would do little to harm what was otherwise expected to be a superb 2014 vintage.

In Napa, a number of building facades crumbled in the historic district, and numerous wine shops were strewn with broken bottles. Most of the red-tagged buildings were damaged despite having been retrofitted to better withstand quakes, officials told a news conference.

Disaster modeling firm CoreLogic estimated that total insured economic losses could range from $500 million to $1 billion, though it acknowledged "a fair amount of uncertainty" around those numbers.

Roughly a quarter to half of that projection could come from residential losses, CoreLogic said, noting that $1.8 billion in insured claims were paid to policyholders after the magnitude 6.9 Loma Prieta earthquake struck San Francisco in 1989.

The Insurance Information Institute in New York likewise estimated that insured quake damage would probably measure in the hundreds of millions of dollars, although overall economic losses will likely run several times higher.

That is because only about 6 percent of Napa area homes are covered by earthquake insurance, said Robert Hartwig, president and economist at the institute.

SPILLED WINE

Parts of Napa's wine industry ground almost to a halt on Monday as workers raced to clean up and salvage their product.

Managers at Napa Barrel Care, which stores product for a number of area vintners, were busy siphoning up spilled wine and scrambling to find barrels to store the spoils until they could disposed of, owner Mike Blom said.