Bluebird Bio Crashes After Clinical Trial Update

Shares of Bluebird Bio, Inc. BLUE are down nearly 35% this morning after the clinical-stage company announced trial results for its LentiGlobin BB305 product, a gene therapy treatment for a rare blood disease.

In its presentation at the American Society of Hematology’s annual meeting, Bluebird said that it has shifted its clinical strategy for the drug, after discovering that it works differently for every patient. Because one result can’t be achieved, the company plans to split up its study populations in new tests.

LentiGlobin BB305 is a therapy to help patients with beta-thalassemia (BT) major. BT is a blood disorder that reduces the production of hemoglobin, the iron-containing protein in red blood cells that carries oxygen throughout the body. Thousands of infants are born with BT each year, and the disorders occurs most frequently in Mediterranean countries, North Africa, the Middle East, Central Asia, India, and Southeast Asia.

Despite the change in trial tactics, Bluebird’s official press release states that it is “safe, feasible and potentially efficacious to treat patients with beta-thalassemia major with LentiGlobin BB305.”

After first introducing BB305 as a solution for BT, shares of Bluebird traded as high as $194. However, the stock lost momentum throughout the trial. Following the latest news, shares have dipped below $60. Bluebird currently has a Zacks Rank #3 (Hold).

Some better ranked stocks in the biomedical field include Achillion Pharmaceuticals ACHN, Anika Therapeutics ANIK, Arena Pharmaceuticals ARNA, and Heska Corporation HSKA.

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