Biotie announces irrevocable subscription undertakings for Convertible Notes from existing shareholders and amends proposals to the Annual General Meeting regarding the relevant authorizations

BIOTIE THERAPIES CORP. STOCK EXCHANGE RELEASE 7 May 2015 at 9.00 a.m.

Not for release, publication or distribution, directly or indirectly, in whole or in part, in or into the United States, Australia, Canada, Japan or South Africa.

Biotie announces irrevocable subscription undertakings for Convertible Notes from existing shareholders and amends proposals to the Annual General Meeting regarding the relevant authorizations

Following the announcement on 23 April 2015 (the "Announcement") by Biotie Therapies Corp. ("Biotie" or the "Company") of its plans to strengthen its capital structure by approximately EUR 95 million, Biotie announces that it has, from certain of its existing shareholders, received irrevocable subscription undertakings for convertible promissory notes, to be issued on the same terms as the US based investors referred to in the Announcement, (together the "Convertible Notes") in the amount of EUR 5.56 million, bringing the total principal amount to be raised from the issuance of the Convertible Notes to EUR 33.06 million. The Company aims to meet the balance of its approximately EUR 95 million funding plan through the planned US public offering (the "US IPO") and potential other offerings in connection with the US IPO.

As previously announced, the subscribers of the Convertible Notes will for each Convertible Note also receive one warrant ("Warrant") which entitles them to subscribe for one new or treasury share in the Company. The irrevocable subscription undertakings received from the existing shareholders are conditional on the granting of the necessary authorizations by the Annual General Meeting of the Company to be held on 26 May 2015 and on the issuance of Convertible Notes to the US based investors referred to in the Announcement having been completed in an amount of no less than EUR 20 million.

Biotie furthermore amends the proposals of the Board of Directors contained in items 16 a) and 16 b) of the invitation to the Annual General Meeting published on 23 April 2015, which relate to the authorization to issue the Convertible Notes and Warrants as well as the issuance of shares thereunder. The proposal in item 16 a) is amended so that the combined aggregate number of new shares and/or treasury shares to be potentially issued by virtue of the special rights entitling to shares under the Convertible Notes and Warrants shall not exceed 442,000,000 shares, which corresponds to approximately 97 per cent of the existing shares and votes in Biotie. In its original form the proposal covered the issuance of at most 562,000,000 shares thereunder. The proposal in item 16 b) is amended so that the said authorization to issue treasury shares would consist of up to 221,000,000 shares in the aggregate. In its original form the proposed authorization covered up to 281,000,000 shares in the aggregate. As a result of the amendment to the proposal in item 16 a), the dilution after the US IPO, as set out in item 16 c) of the invitation to the Annual General Meeting published on 23 April 2015, is also technically amended. The amended invitation to the Annual General Meeting has been attached hereto in its entirety. The proposals relating to the agenda of the Annual General Meeting as well as the invitation are also available on Biotie Therapies Corp.`s website at www.biotie.com.