In This Article:
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Allowed US patent application for anti-TNFR2 antibody BI-1910 covers composition-of-matter protection and the use of antibody to treat cancer
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Patent will further strengthen IP protection of BioInvent's innovative portfolio of clinical assets
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BI-1910 is being studied in a Phase 1/2a trial as both a single agent and in combination with KEYTRUDA® for the treatment of solid tumors
LUND, SWEDEN / ACCESSWIRE / July 30, 2024 / BioInvent International AB ("BioInvent") (Nasdaq Stockholm:BINV)(STO:BINV), a biotech company focused on the discovery and development of novel and first-in-class immune-modulatory antibodies for cancer immunotherapy, today announced that the US Patent and Trademark office (USPTO) has issued a Notice of Allowance for a patent application relevant to the anti-TNFR2 antibody BI-1910 by the
The patent, once granted, provides a composition-of-matter protection for BI-1910 and the use of the antibody for the treatment of cancer.
"The allowance of this patent application underlines the unique features and proprietary nature of the BI-1910 antibody, building on the potential the asset is already demonstrating in its clinical development," said Martin Welschof, Chief Executive Officer of BioInvent. "We are committed to establishing a robust intellectual property portfolio around our innovative immuno-oncology pipeline, and we welcome the additional protection this patent will afford to our TNFR2 program in particular."
About BI-1910
BI-1910 is BioInvent's second tumor necrosis factor receptor 2 (TNFR2) program, currently in Phase 1 clinical development, after BI-1808 in Phase 2a. BI-1910 displays a differentiated, agonist approach to cancer treatment compared to BI-1808, BioInvent's first-in-class anti-TNFR2 antibody. Both monoclonal antibodies were chosen as potential best-in-class, from a large family of binders generated through BioInvent's proprietary F.I.R.S.T™ technology platform. It is being studied as both a single agent and in combination with MSD's (Merck & Co., Inc., Rahway, NJ, USA) anti-PD-1 therapy KEYTRUDA (pembrolizumab) in patients with advanced solid tumors. The single agent arm of the Phase 1/2a BI-1910 study was initiated in December 2023 and first data is expected by H2 2024.
About BioInvent
BioInvent International AB (Nasdaq Stockholm: BINV) is a clinical-stage biotech company that discovers and develops novel and first-in-class immuno-modulatory antibodies for cancer therapy, with currently five drug candidates in six ongoing clinical programs in Phase 1/2 trials for the treatment of hematological cancer and solid tumors. The Company's validated, proprietary F.I.R.S.T™ technology platform identifies both targets and the antibodies that bind to them, generating many promising new immune-modulatory candidates to fuel the Company's own clinical development pipeline and providing licensing and partnering opportunities.