Autolus Therapeutics plc (AUTL): A Bull Case Theory

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We came across a bullish thesis on Autolus Therapeutics plc (AUTL) on wallstreetbets Subreddit Page by _Ukey_. In this article, we will summarize the bulls’ thesis on AUTL. Autolus Therapeutics plc (AUTL)'s share was trading at $3.20 as of Dec 3rd.

A scientist in a laboratory, working on developing a new cancer therapy.

Autolus Therapeutics is a biopharmaceutical company focused on developing innovative CAR-T cell therapies for the treatment of various cancers. Its flagship product, Aucatzyl (obecabtagene autoleucel), has recently gained attention with its FDA approval on November 8, 2024, for the treatment of adult patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (r/r B-ALL). This approval marks a significant achievement for the company, positioning Aucatzyl as a promising new treatment option in the competitive CAR-T therapy market. The approval is supported by strong clinical data from the pivotal Phase 1b/2 FELIX study, which demonstrated an impressive 76.6% overall response rate, coupled with a low incidence of severe immune-related toxicities, further solidifying the therapy’s potential in the oncology space.

Financially, Autolus has seen substantial improvements in its cash position, with cash and cash equivalents increasing to $657.1 million as of September 30, 2024, up from $239.6 million at the end of 2023. This robust cash position, which has been bolstered by recent funding and investments, is expected to support the commercialization of Aucatzyl in r/r B-ALL as well as the advancement of the company’s broader pipeline of therapies. However, despite these positive developments, Autolus has also faced challenges. In Q3 2024, the company reported total operating expenses of $67.9 million, a significant increase from $42.9 million in the same period of 2023. As a result, the company posted a net loss of $82.1 million for Q3 2024, compared to $45.8 million in Q3 2023. These losses highlight the ongoing challenges in managing costs while advancing clinical and commercial operations. Nonetheless, Autolus believes its current cash reserves are sufficient to fund its key priorities, including the full launch of Aucatzyl.

On the technical side, the stock has shown mixed signals. While it is trading above its short-term and long-term moving averages, suggesting a potential bullish trend, other indicators, such as the Relative Strength Index (RSI) and the Stochastic Oscillator, suggest that the stock may be approaching oversold conditions, indicating potential upside. The Moving Average Convergence Divergence (MACD) is also below the signal line, indicating bearish momentum. Support and resistance levels have been identified, with support at $2.80 and resistance at $3.50. A breakout above $3.50 could signal a bullish reversal, while a drop below $2.80 could indicate further declines.