Asian shares fell on Thursday after a mixed start, amid uncertainty over the U.K.'s exit from the European Union, as the dollar strengthened and crude oil prices slipped.
Japan's Nikkei 225 (Nihon Keizai Shinbun: .N225) slipped 0.17 percent, likely due to prolonged yen strength. The yen is seen as a safe-haven currency, but a stronger yen is generally negative for many Japanese companies as export earnings are reduced.
Shares of Toshiba t (Tokyo Stock Exchange: 6502.T-JP)urned positive, up 0.27 percent, ahead of an extraordinary shareholders meeting . The Japanese conglomerate's U.S. subsidiary Westinghouse Electric filed for bankruptcy on Wednesday, after it posted a multi-billion dollar write-off due to cost overruns at four nuclear reactors under construction in the U.S.
The ASX 200 (^AXJO) rose 0.36 percent, led by its materials and energy sub-indexes.
In South Korea, the Kospi (Korea Stock Exchange: .KS11) index slipped from the green, to trade down 0.04 percent.
Samsung Electronics (Korea Stock Exchange: 593'A-KR), which released its Samsung Galaxy S8 smartphone in South Korea today, was up 1.2 percent. The latest model is the company's first premium smartphone since its September recall of all Galaxy Note 7 devices due to its fire-prone batteries.
The Shanghai composite (Shanghai Stock Exchange: .SSEC) was down 0.07 percent and Shenzhen composite (Dow Jones Global Indexes: .DJSZ) fell 0.21 percent. Hong Kong's Hang Seng (Hong Kong Stock Exchange: .HSI) index was up 0.04 percent.
The dollar broke above the 100 handle, to trade at 100.06 against a basket of currencies, after trading below for eight sessions. Against the greenback, the yen was weaker at 111.38 and the Australian dollar was at $0.7673.
U.S. equities closed mostly higher on Wednesday, led by energy.
The Dow Jones industrial average fell 0.2 percent to close at 20,659.32, the S&P 500 rose 2.56 points to end at 2,361.13. The Nasdaq composite closed up 0.38 percent at 5,897.55. Over in Europe, stocks closed higher on Wednesday as investors remained calm over Britain's Brexit proceedings.
The pound and the euro both fell against the dollar when the official letter triggering Article 50 was handled to European Council President Donald Tusk.
At 9:35 am HK/SIN, the pound (:GBPUSD=)traded at $1.2449, lower than highs seen at 1.2460 seen yesterday but the euro (Unknown:EURBA=)eased to $1.0754, compared to yesterday's highs of $1.0814.
"The weakness in sterling was directly related to all the uncertainty and questions that we know have, after the U.K. began these proceedings. There's a lot more questions than answers, I do believe that we could see further sterling weakness," Kathy Lien, managing director at BK Asset Management told CNBC.