3 Richly Valued Stocks I'll Be Watching Like a Hawk in 2025

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Investing in stocks with high valuations isn't necessarily a bad decision, but it's something to be done deliberately and with caution. Today, the market's average price-to-earnings (P/E) multiple is around 30.6. So stocks with P/E ratios that are higher than that might be a bit overvalued -- or perhaps opportunities to pay a premium for a high-quality investment.

This year, I'm going to be particularly watching three companies with valuations on the higher side, and you might want to as well. Even if you don't buy them, they're probably worth tracking. Here's why.

1. Eli Lilly

As the creator of the blockbuster weight-loss drug Zepbound, and the blockbuster type 2 diabetes drug Mounjaro, Eli Lilly (NYSE: LLY) is exposed to a tremendous amount of opportunity. But with a P/E of 79, few would call its shares a bargain.

The question is whether it can continue to sustain its relatively rapid growth long enough that those who buy it today could get a good return. For reference, its trailing-12-month operating income is up by an impressive 71% in the last three years, reaching $15.1 billion. Nonetheless, new evidence suggests that the bull thesis is starting to become a bit tempered, rather than more exuberant.

On Jan. 14, Lilly published updated guidance for the 2024 calendar year, indicating that revenue in the fourth quarter would fall roughly $400 million beneath the floor of $13.5 billion that it had provided in prior guidance to investors. Responsible for the underperformance: weaker-than-anticipated sales growth of the very medicines that management hopes will drive the pharma's growth in 2025 -- Zepbound and Mounjaro.

This issue may just be a blip, and that's certainly what management is trying to signal. If it isn't, and the growth of those two drugs continues to be slower than expected for another couple of quarters, it'll be a sign that the stock is too expensive to be worth buying. In contrast, if growth accelerates back to where it was expected to be, it'll be an affirmation of the investment thesis for the stock, even at its present valuation.

2. Costco Wholesale

As it's one of my favorite stocks, I'm always interested to hear about what's going on with Costco Wholesale (NASDAQ: COST) despite its current P/E of 55.7, and I plan to keep accumulating it for as long as it continues to perform well. Over the last 10 years, its trailing 12-month net income climbed by 234%, reaching $7.6 billion, and I anticipate that pace continuing.

But there are two reasons that I watch this investment a bit more closely than I usually would. The first is that Costco has a new CEO, Ron Vachris, who has worked in various roles in the business for more than 40 years. To evaluate this CEO's performance and its probable impact on the company's trajectory, it's necessary to pay attention to what he does and the rationale he provides for it.