These 2 Monster Growth Stocks Skyrocketed Over 1,000% This Year — Here’s What Analysts Expect in 2025

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“Past performance won’t guarantee future returns” is one of the first lessons in investing, a useful reminder that we can never tell what the future has in store. At the same time, a strong track record for a particular company can also suggest that the good times just might keep on rolling.

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So, what does it mean when a stock gains 1,000% or more in a single year? A jump of that magnitude signifies sustained outperformance – and investors will rightly wish to take a closer look. Wall Street’s analysts also pay close attention to such robust gains, digging into the financials to understand what’s really going on.

We’ve opened up the TipRanks database to look at two monster growth stocks that have skyrocketed over 1,000% this year to understand what the analysts are expecting from them in 2025. Here’s what we found.

Monopar Therapeutics, Inc. (MNPR)

First on our list of growth stocks today is Monopar Therapeutics, a biotech research firm working at both the preclinical and clinical research stages in the development of new treatments for cancer and a rare genetic disease. The company notes that cancer will affect nearly half of the population at some time, while its own management team possesses idiosyncratic expertise in the treatment of a rare genetic condition, Wilson’s disease, in which the body is unable to remove excess copper.

Following these tracks, Monopar has developed MNPR-101, a set of related variations on a novel, first-in-class humanized monoclonal antibody designed to target the urokinase plasminogen activator receptor, or uPAR. This is a well-characterized protein receptor frequently implicated in tumor cells and expressed in a wide range of tumor tissues. Due to the low expression of uPAR in normal tissues, the company believes that MNPR-101 has the potential to become a well-tolerated treatment for a large number of cancers.

The company has also recently acquired an exclusive worldwide license for ALXN-1840. Monopar acquired this license from Alexion, Astra Zeneca Rare Disease. ALXN-1840 has completed a Phase 3 trial in the treatment of Wilson’s disease, and Monopar will conduct future activities in global development and commercialization of the drug. The acquisition of ALXN-1840 was made through an undisclosed cash payment by Monopar, along with agreement to pay future royalties based on sales and other milestones. In addition to its license, Monopar has an equity stake in ALXN-1840.