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Karyopharm Therapeutics Inc. (KPTI)

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3.8600
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At close: April 4 at 4:00:03 PM EDT
3.8600
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After hours: April 4 at 7:22:56 PM EDT

Key Executives

Amounts are as of December 31, 2023 and compensation values are for the last fiscal year ending on that date. Pay is salary, bonuses, etc. Exercised is the value of options exercised during the fiscal year. Currency in USD.
NameTitlePayExercisedYear Born
Mr. Richard A. Paulson M.B.A. President, CEO & Director 1.43M -- 1967
Ms. Sohanya Cheng M.B.A. Executive VP, Chief Commercial Officer & Head of Business Development 742.95k -- 1983
Mr. Stuart Poulton Executive VP & Chief Development Officer 682.48k -- 1973
Dr. Reshma Rangwala M.D., Ph.D. Executive VP, Chief Medical Officer & Head of Research 777.32k -- 1979
Dr. Mansoor Raza Mirza M.D. Clinical Consultant, Member of Scientific Advisory Board & Independent Director 150k -- 1961
Dr. Sharon Shacham M.B.A., Ph.D. Co-Founder & Chairman of Scientific Advisory Board 1.4M -- 1970
Ms. Lori A. Macomber CPA EVP, CFO & Treasurer -- -- 1972
Ms. Kristin Abate VP, Chief Accounting Officer & Assistant Treasurer -- -- --
Mr. Brendan Twohig Strong SVP of Investor Relations & Corporate Communications -- -- --
Mr. Michael J. Mano J.D. Senior VP, General Counsel & Secretary 625.08k -- 1978

Karyopharm Therapeutics Inc.

85 Wells Avenue
2nd Floor, Suite 210
Newton, MA 02459-3298
United States
617 658 0600 https://www.karyopharm.com
Sector: 
Healthcare
Industry: 
Biotechnology
Full Time Employees: 
279

Description

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also developing Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating Myelodysplastic Neoplasms, as well as verdinexor, KPT-9274, and IL-12 compounds. In addition, the company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, the company has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed/refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Corporate Governance

Karyopharm Therapeutics Inc.’s ISS Governance QualityScore as of April 1, 2025 is 7. The pillar scores are Audit: 4; Board: 8; Shareholder Rights: 8; Compensation: 7.
Corporate governance scores courtesy of Institutional Shareholder Services (ISS) Scores indicate decile rank relative to index or region. A decile score of 1 indicates lower governance risk, while a 10 indicates higher governance risk.

Upcoming Events

May 6, 2025 at 12:30 PM UTC - May 12, 2025 at 12:30 PM UTC

Karyopharm Therapeutics Inc. Earnings Date

Recent Events

February 24, 2025 at 12:00 AM UTC

8-K: Corporate Changes & Voting Matters

February 19, 2025 at 12:00 AM UTC

10-K: Periodic Financial Reports

January 31, 2025 at 12:00 AM UTC

8-K: Corporate Changes & Voting Matters

January 30, 2025 at 12:00 AM UTC

8-K: Corporate Changes & Voting Matters

January 13, 2025 at 12:00 AM UTC

8-K: Corporate Changes & Voting Matters

January 2, 2025 at 12:00 AM UTC

8-K: Corporate Changes & Voting Matters

December 16, 2024 at 12:00 AM UTC

DEF 14A: Proxy Statements

December 3, 2024 at 12:00 AM UTC

8-K: Corporate Changes & Voting Matters

November 20, 2024 at 12:00 AM UTC

8-K: Corporate Changes & Voting Matters

November 8, 2024 at 12:00 AM UTC

8-K: Corporate Changes & Voting Matters

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