The S&P 500 and Nasdaq (^DJI, ^GSPC, ^IXIC) are taking off to new all-time highs, as crude oil gives the energy sector a much needed boost. Catch The Final Round at 4 p.m. with Jen Rogers and Yahoo Finance Editor-in-Chief Andy Serwer.

Winners and losers

Stocks getting hit today include Viacom as analysts at both BMO and RBC cut their price targets; Ionis Pharmaceuticals on concerns over side effects for an experimental nerve disease treatment; and Exact Sciences, with shares of the medical diagnostics company tumbling after short-seller Citron Research criticized the company’s Cologuard colon cancer test as a “seriously inferior product.”

Stocks getting a boost today include FireEye as concerns over the Wannacry ransomware virus lifted shares of it and other cybersecurity firms; Cisco as Morgan Stanley upgraded shares of the world’s largest networking company to overweight; and Patheon, with shares of the drug ingredient maker surging after biotech company Thermo Fisher Scientific agreed to buy it for $7.2 billion, including debt.

Whale watching: Breaking down 13-F season

What are the big Wall Street whales holding? Yahoo Finance’s Julia La Roche is here with all the latest from 13-F season, where big fund managers need to disclose their stakes from the past quarter.

Looking ahead

• At 8:30 a.m. ET, we’ll get housing starts for April. The consensus estimate is for a seasonally adjusted 1.25 million new starts, slightly more than the prior month.

• At 9:15 a.m. ET, the Fed releases industrial production figures for April. The Street’s expecting production to rise 0.4%, slight less than the March reading.

• Finally, we’ll get earnings reports from Dow component Home Depot, Dicks Sporting Goods and Staples.